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🧃 Probiotics and Constipation

Which Probiotics Are Effective?

2 min read · Clinician-reviewed

When it comes to using probiotics for childhood constipation, the specific strain of bacteria is very important. Not all probiotics are the same, and different strains can have different effects on the gut. While the overall evidence for probiotics in treating constipation is still developing, some strains have been studied more than others and have shown more promise.

Strains with Some Positive Evidence

Research has suggested that certain strains of Lactobacillus and Bifidobacterium may be helpful for some children with constipation.

  • Lactobacillus reuteri: Some studies have found that this strain can help increase the frequency of bowel movements in infants and children with functional constipation [1].
  • Bifidobacterium breve: This strain has also been shown in some studies to improve stool frequency and consistency in constipated children [2].
  • Lactobacillus rhamnosus GG (LGG): This is one of the most widely studied probiotic strains. While some studies have shown a benefit when used in combination with laxatives, others have found it to be no more effective than a placebo on its own [3].

As an additional bacterial genus, Akkermansia muciniphila is a next-generation probiotic candidate that may improve gut barrier function and reduce low-grade inflammation, but its role in treating constipation remains unproven. Early human trials show safety and metabolic benefits, yet evidence of clear clinical efficacy is still limited.

It is important to note that many studies use a combination of different probiotic strains, making it difficult to determine which specific one is responsible for the effects.

What to Look for in a Probiotic Supplement

If you and your healthcare provider decide to try a probiotic for your child, look for a product that clearly lists the specific strains and the number of colony-forming units (CFUs) in each dose. A product with a strain that has been studied for constipation is a reasonable choice. However, it is crucial to remember that what works for one child may not work for another.

The field of probiotic research is rapidly evolving, and more studies are needed to make definitive recommendations. Always consult with a healthcare provider before starting any new supplement.

References

  1. 1. Guerra PV, Lima LN, Souza TC, et al. Pediatric functional constipation treatment with Bifidobacterium-containing yogurt: a crossover, double-blind, controlled trial. World J Gastroenterol. 2011 Sep 14;17(34):3916-21. doi: 10.3748/wjg.v17.i34.3916.
  2. 2. Tabbers MM, de Milliano I, Roseboom MG, Benninga MA. Is Bifidobacterium breve effective in the treatment of childhood constipation? Results from a pilot study. Nutr J. 2011 Feb 23;10:19. doi: 10.1186/1475-2891-10-19.
  3. 3. Wojtyniak K, Szajewska H. Systematic review: probiotics for functional constipation in children. Eur J Pediatr. 2017;176(9):1155-1162. doi:10.1007/s00431-017-2972-2.
  4. 4. Ottria R, Xynomilakis O, Casati S, Ciuffreda P. Pre- to Postbiotics: The Beneficial Roles of Pediatric Dysbiosis Associated with Inflammatory Bowel Diseases. Microorganisms. 2024 Aug 2;12(8):1582. doi: 10.3390/microorganisms12081582.
  5. 5. Zhao Y, Yang H, Wu P, Yang S, Xue W, Xu B, Zhang S, Tang B, Xu D. Akkermansia muciniphila: A promising probiotic against inflammation and metabolic disorders. Virulence. 2024 Dec;15(1):2375555. doi: 10.1080/21505594.2024.2375555. Epub 2024 Aug 27.