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💊 Medications in Treatment

Does Constipation Return When the Medication Is Stopped?

2 min read · Clinician-reviewed

Yes, it is very common for constipation to return if laxative medication is stopped too soon. This is one of the most frequent reasons for treatment failure in childhood constipation. Relapse is not a sign that the medication has failed, but rather an indication that the underlying issues have not yet fully resolved.

Why Does Constipation Recur?

Chronic constipation causes the rectum and colon to stretch. It takes a significant amount of time for these organs to return to their normal size and for the nerves that signal the need to defecate to regain their sensitivity. If laxatives are stopped before the bowel has had a chance to fully recover, it is easy for stool to begin to accumulate again, starting the cycle of constipation all over.

Furthermore, if the child has not yet overcome the fear of painful bowel movements and has not established solid, regular toileting habits, they are more likely to begin withholding stool again once the medication is stopped. A study on the long-term prognosis of childhood constipation found that about half of the children who were successfully treated still experienced relapses [1].

Preventing Relapse

The key to preventing relapse is to wean off medication very slowly and only after a prolonged period of success. Success is typically defined as the child having regular, soft, pain-free bowel movements without any fecal incontinence for at least one month.

The weaning process should be guided by a healthcare provider and should be accompanied by continued attention to diet, fluid intake, and behavioral routines. If symptoms of constipation start to return during the weaning process, the dose of medication may need to be increased again for a period of time before attempting to wean again.

Patience is crucial. It is better to continue treatment for a longer period and have a successful outcome than to stop too early and have to start the entire process over.

References

  1. 1. Bongers ME, van Wijk MP, Reitsma JB, Benninga MA. Long-term prognosis for childhood constipation: clinical outcomes in adulthood. Pediatrics. 2010 Jul;126(1):e156-62. doi: 10.1542/peds.2009-1009.
  2. 2. Tabbers MM, DiLorenzo C, Berger MY, et al. Evaluation and Treatment of Functional Constipation in Infants and Children: Evidence-Based Recommendations From ESPGHAN and NASPGHAN. J Pediatr Gastroenterol Nutr. 2014;58(2):258–274. doi:10.1097/MPG.0000000000000266.
  3. 3. Ho JMD, How CH. Chronic constipation in infants and children. Singapore Med J. 2020 Feb;61(2):63-68. doi: 10.11622/smedj.2020014.